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A 163-FOOT

mural showcases the scientific process Forge Biologics uses to manufacture life-saving gene therapies

cGMP Manufacturing Facility and Office Expansion

01 Challenge

Forge Biologics, a Columbus-based development engine accelerating the advancement of gene therapies, enlisted BHDP’s planning, engineering, and architectural services for The Hearth—a more than 200,000-SF building with a custom-designed cGMP facility dedicated to AAV viral vector manufacturing. Their facility required a multi-phase design, which included a cGMP buildout, development and analytical labs, and a 50,000-SF office.

02 Solution

After gaining valuable information in our Understand phase of Forge Biologics' conceptual master plan, BHDP developed a phased approach for the cGMP cleanroom buildout. The Forge master plan included each phase as a separate tuning fork with every suite designed for ISO 7 conditions. The cleanroom layout is self-contained and helps drive unidirectional workflow to support operations. Since each tuning fork can function separately, the phasing allowed for expansion while maintaining current operations. 

Quick Facts

Completion Date 2022

Size 200,000 SF

Location Columbus, OH